Pure Methylation

You can take methylation in the form of a handful of B vitamins, because the mutation is not just affecting methyl groups but also the enzyme Folate Reductase which methylate’s Folate. Pure Methylation is the combination of 3 B Vitamins: B12, B6, and Folate.

Why do a balanced B? If what you need is folate and you need it to be methylated, then why add a B12 and a B6?

Bodies work in ratios. They aren’t designed to work on a single B vitamin or any single nutrient for that matter. Think about foods with lots of B vitamins such as leafy green vegetables. You never find just one B vitamin, and this is because the mitochondrial cycle requires a number of B’s in a very specific ratio. Therefore, we use Pure Methylation in our clinic and recommend it to individuals with MTHFR mutations. Pure Methylation is the combination of 3 B Vitamins: B12, B6, and Folate and adheres to the same ratio that the mitochondrial cycle prefers with the already reduced form of the vitamin folate. This means it’s easy to absorb if you have MTHFR mutations.

Keep in mind; methylation is a tool that the body uses to turn on and turn off reactions. It is a promoter, it turns on sequences. Do not with any methylation, including this product or any other supporting methylation, don’t take too much of it. If you over methylate, a whole bunch of different reactions in the body are created that can’t be controlled.

The key when picking out a product concerning methylation is to make sure that its pure and certified specifically for MTHFR. MTHFR bodies DO NOT like toxicity. Make sure it is a very clean physician grade vitamin such as our Pure Methylation. You also want to make sure you have the right ratio of B vitamins. Just taking a methylated folate can be a problem because the mitochondrial cycle is turned on by B12. Only driving one part of this cycle without the rest can create problems for the body.
If you’re looking for a safe product for effective methylation with the right balance of B vitamins and a clean product that’s easily absorbable, then we recommend Pure Methylation.

Pure Methylation, what is it? (Transcript from video)

This is probably one of my favorite products for MTHFR, and you can see, under 'biome IQ', it has the MTHFR Family logo over there, meaning it's certified and safe, and designed for MTHFR. It's the combination of three B vitamins, so it's B12, B6, and folate. And I'm sure you're going to ask the question, "Is it the right folate for MTHFR? So, is it a five prime methyltetrafolate?" It absolutely is. If you want to learn more about this product, more about the specifics, the technical side of things, just click on the next video.

 

Tech Talk (Transcript from video)

Pure methylation. Let's get down and dirty with the technical reason why this product works. So, I know most folks at MTHFR are keenly aware that what they really have is a deficiency in methylation, not making enough methylation as well as a difficulty producing properly the enzyme folate reductase. All right, so, it means that it gets dirty very fast. That's really the bottom line. And so, most of the symptoms associated with MTHFR are not a result of the mutation but acquiring lots of toxins that then cause hormone dysregulations and just generally make you sick.

So, the question is how do you get rid of those toxins, or basically, how do you make up for the methylation deficiency? Well, you can take methylation in the form of a handful of B vitamins because the mutation is not just methyl group, but also the enzyme folate reductase methylating the vitamin folate. Of course, becomes the holy grail for MTHFR, right? So, why do a balanced B? If what you need is folate and you need to be methylated, why add a B12 and a B6? So here's the thing, bodies work in ratios. They're not designed to work just on a single B vitamin. And if you think about foods that have lots of B vitamins like green vegetables, you never really find a vitamin that has just one B, and it's because the cycle, the mitochondrial cycle requires a number of these in a very specific ratio.

The reason I like this product over here is because, it adheres to the same ratio that the mitochondrial cycle prefers, with the already reduced form of the vitamin folate, meaning it's easy to absorb if you have MTHFR. One word of caution for everybody, I know, again, because you have MTHFR, and you probably read a lot about it, you're thinking, "Maybe let me methylate, and then let me methylate some more to keep feeling better." Keep in mind, methylation is a tool that a body uses to turn on and turn off reactions.

It is by definition, a promoter, turns on sequences. Do not, with any methylation that's true for pure methylation, it's true for any methylation, don't take too much of it. If you over-methylate, you create a whole bunch of reactions in a body that it can't control. So the key when you're picking up your own product for methylation, this one's mine, number one, you wanna make sure it's pure and certified specifically for MTHFR. MTHFR bodies don't like toxicity, so you wanna make sure it's a very, very clean nutraceutical, so physician grade Vitamin, which this one is. Number two, you wanna make sure that you get the right ratio of B vitamins. So just taking a methylated folate can be a problem because the cycle is actually turned on by B12. So if you just drive one part of the cycle without the rest, body's gonna have a problem

And then finally, depending on your MTHFR methylation, that's how you know how many of these pills to take. Here in clinic, what we normally do is a single A mutation. So A in a wild tape. We normally make the recommendation of one cap per day for a double C mutation, so least affected to most affected. A by itself or a double C the two sides of the spectrum for MTHFR. For a double C, depending on the person, depending on the symptoms, depending on their labs, what we normally recommend is two caps up to two times per day. All right, so again, if you're looking for a safe product for effective methylation, the balance of the B vitamins over here, the fact that it's such a clean product, the fact that it's so good at really driving that mitochondrial cycle, it's my favorite when it comes to methylation.